Simons Centre for the Study of Living Machines

We study molecules, cells, and organisms as living machines: products of natural selection which consume energy to achieve specific goals. Our research combines theory and experiment, and covers a range of length and timescales: from protein function, computational cell biology and evolution, to the physics of active systems.

We are supported by the National Centre for Biological Sciences and the Simons Foundation.


Finding Needles in Genomic Haystacks
18th Jan 2019
Rob Phillips
Physical Biology of the Cell
14th Jan 2019
Prof. Rob Philips, Caltech
10th Jan 2019
Mukund Thattai
The coming of age of de novo protein design
1st Jan 2019
David Baker


S. Vishen; J.F. Rupprecht; G.V. Shivashankar; J. Prost; M. Rao. 2018
Physical Review EPhys. Rev. E.97(3)

J.F. Rupprecht; S. Vishen; G.V. Shivashankar; M. Rao; J. Prost. 2018
Physical Review LettersPhys. Rev. Lett..120(9)

S. Chib; S. Das; S. Venkatesan; A.Sai Narain Seshasayee; M. Thattai. 2018
New Journal of Physics.20(3):035004

S.Kumar Nandi; R. Mandal; P.Jyoti Bhuyan; C. Dasgupta; M. Rao; N.S. Gov. 2018
Proceedings of the National Academy of Sciences.115(30):7688

Cellular Communities

We aim to combine experimental and theoretical methods to understand the collective dynamical behavior of populations. Ex. competition and cooperation in bacteria


Molecular and Cellular Dynamics

A large part of our effort at the Simons Centre is in exploring new physical and chemical principles underlying biological organization across scales


Computer Science Interface

This interface theme links all the activities of the Simons Centre with computer science and biology. We hope to play a critical role in nurturing this interface.

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