Simons Centre for the Study of Living Machines


We study molecules, cells, and organisms as living machines: products of natural selection which consume energy to achieve specific goals. Our research combines theory and experiment, and covers a range of length and timescales: from protein function, computational cell biology and evolution, to the physics of active systems.

We are supported by the National Centre for Biological Sciences and the Simons Foundation.

Publications

S. Varahan; A. Walvekar; V. Sinha; S. Krishna; S. Laxman. 2019
bioRxiv.

V. Datta; S. Hannenhalli; R. Siddharthan. 2019
PLOS Computational Biology.15

N.Manuel Mascarenhas; V.L. Terse; S. Gosavi. 2018
The Journal of Physical Chemistry BThe Journal of Physical Chemistry B.122(6)

S. Krishna; S. Laxman; D.J. Lew. 2018
Molecular Biology of the CellMolecular Biology of the Cell.29(19)

Cellular Communities

We aim to combine experimental and theoretical methods to understand the collective dynamical behavior of populations. Ex. competition and cooperation in bacteria

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Molecular and Cellular Dynamics

A large part of our effort at the Simons Centre is in exploring new physical and chemical principles underlying biological organization across scales

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Computer Science Interface

This interface theme links all the activities of the Simons Centre with computer science and biology. We hope to play a critical role in nurturing this interface.

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