Simons Centre for the Study of Living Machines


We study molecules, cells, and organisms as living machines: products of natural selection which consume energy to achieve specific goals. Our research combines theory and experiment, and covers a range of length and timescales: from protein function, computational cell biology and evolution, to the physics of active systems.

We are supported by the National Centre for Biological Sciences and the Simons Foundation.

Events

7th Annual Monsoon School Jun 17 - Jun 26, 2019
17th Jun 2019
Madan Rao, Mukund Thattai, Sandeep Krishna, Shachi Gosavi, Shashi Thutupalli
Cell-Matrix Interactions in Cancer and Fibrosis: Multiscale Chemo-Mechanical Models
17th Apr 2019
Vivek Shenoy
Molecular motors interacting with actin filaments
9th Apr 2019
Jean-François Joanny
Functional views of evolutionary constraints in gene networks
27th Mar 2019
Philippe Nghe

Publications

S. Varahan; A. Walvekar; V. Sinha; S. Krishna; S. Laxman. 2019
bioRxiv.

V. Datta; S. Hannenhalli; R. Siddharthan. 2019
PLOS Computational Biology.15

V.V.Hemanth Rao; S. Gosavi. 2018
Proceedings of the National Academy of Sciences.115(9):1998

S. Thutupalli; D. Geyer; R. Singh; R. Adhikari; H.A. Stone. 2018
Proceedings of the National Academy of Sciences.115(21):5403

Cellular Communities

We aim to combine experimental and theoretical methods to understand the collective dynamical behavior of populations. Ex. competition and cooperation in bacteria

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Molecular and Cellular Dynamics

A large part of our effort at the Simons Centre is in exploring new physical and chemical principles underlying biological organization across scales

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Computer Science Interface

This interface theme links all the activities of the Simons Centre with computer science and biology. We hope to play a critical role in nurturing this interface.

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