Naturally occuring populations of cells, whether genetically identical or composed of multiple species or strains, typically exhibit a wide range of phenotypic diversity. We aim to combine experimental and theoretical methods to understand the collective dynamical behaviour of such populations; for example: competition and cooperation in bacterial biofilms, periodic waves of growth and quiescence in yeast populations, the coevolution of viruses and bacterial defenses, and the evolution of multicellularity and hybrid cellular species.
Events
Discussion Meeting on Emergence and Evolution of Biological Complexity 4th Feb 2017 Sandeep Krishna (NCBS), Clement Nizak, Philippe Nghe, Sandeep Ameta (ESPCI, Paris), Sudha Rajamani (IISER Pune) |
PUBLICATIONS
Dey, Gautam, Mukund Thattai, and Buzz Baum. “On the Archaeal Origins of Eukaryotes and the Challenges of Inferring Phenotype from Genotype.” Trends in Cell Biology 26.7 (2016): 476–485. PMC. Web. 15 Sept. 2016.
Restriction Modification Systems as Engines of Diversity,. Sneppen, K.; Semsey, S.; Seshasayee, A.; and Krishna, S. Front. Microbiol., 6: 528. 2015.
Why do bacteria regulate public goods by quorum sensing?-How the shapes of cost and benefit functions determine the form of optimal regulation,. Heilmann, S.; Krishna, S.; and Kerr, B. Front. Microbiol., 6: 767. 2015.
Restriction Modification Systems as Engines of Diversity,. Sneppen, K.; Semsey, S.; Seshasayee, A.; and Krishna, S. Front. Microbiol., 6: 528. 2015.
Why do bacteria regulate public goods by quorum sensing?-How the shapes of cost and benefit functions determine the form of optimal regulation,. Heilmann, S.; Krishna, S.; and Kerr, B. Front. Microbiol., 6: 767. 2015.