Ichizo Kobayashi is a distinguished professor at the University of Tokyo. His primary research interest lies in restriction-modification systems in bacteria. In 1995 he showed that restriction-modification systems in bacteria are selfish, addiction modules. He has also made major contributions to the functioning of bacterial DNA repair systems. His current interest is in the evolution of restriction-modification systems. This fits very well with the interests of Aswin Seshasayee and Sandeep Krishna who have published recently on restriction-modification systems, and would like to collaborate with Prof. Kobayashi on experiments and modelling studies of the evolution of these systems. At NCBS Prof. Kobayashi would also be interested in interacting with P. Shivaprasad to develop new research projects to study the similarities and differences in epigenetics-mediated adaptive evolution in plants vs bacteria.